Liverpool supporters joked Conor Bradley's own-goal was reminiscent of Jamie Carragher following their 5-1 win over Sparta Prague.
The Reds seized the initiative in the Czech capital, taking the lead within five minutes after Alexis Mac Allister opened the scoring from the penalty spot.
Darwin Nunez added to their advantage with a brace before the interval, marking the 1000th goal of Jurgen Klopp's tenure at the club in the process.
Klopp opted to make a change at half-time, with Bradley brought on to replace Joe Gomez.