Liverpool asked Premier League chiefs to move their next match at Watford to an evening kick-off in a bid to make Alisson, Fabinho and Roberto Firmino available after international duty - but it was turned down by their opponents.
The Telegraph report that Watford opposed the request, arguing that fans will have already arranged travel plans and that it would be an inconvenience to them.
The Brazilian trio of Liverpool players have been called up to their national team this week, and are set to face Uruguay barely 24 hours before the Watford game.