The FA Women’s Championship fixture kicks off at 2pm BST on Sunday September 12 at Prenton Park.
Bristol played in the Women’s Super League last season and Reds boss Matt Beard spent the second half of the campaign as interim manager there.
It will also be a reunion for Liverpool players Carla Humphrey, Jasmine Matthews and Yana Daniels, who all joined from Bristol in the summer.
Tickets for the game are on sale now, priced £6.50 for adults and £4 for concessions. Wheelchair access can also be booked.