The venue switch for the Women’s Super League fixture follows the ongoing difficulties with the pitch at the team’s current home, Tranmere Rovers’ Prenton Park.
LFC and Chester have a long-standing relationship and the Reds’ U23s have played many games at the Deva in recent years. Most recently, the club’s U18s played there on the way to lifting the FA Youth Cup in 2019.
Jürgen Klopp also brought the Liverpool first team to the stadium in the pre-season of 2018, with a crowd of almost 4,500 in attendance.
LFC chief executive officer Peter Moore, chair of Liverpool FC Women, said: “It’s fantastic that we are able to continue our excellent relationship with Chester FC and we hope as many fans as possible will take this terrific opportunity to see the Liverpool Women play.