The meeting of two of football’s traditional rivals sees the Reds seek to move away from the foot of the WSL table while fourth placed United will look to rebound from a shock 1-0 defeat to Bristol City last weekend.
LFC Women manager Vicky Jepson is hoping for a big crowd to cheer on her team with narrow margins continuing to frustrate the search for a first league win.
In her programme notes for the game, Jepson says: "We know that United have got so much class in their team and they’ve got a great leader in Casey (Stoney) so we understand that we’re going to get fully tested.