The former picked up a knock during the 4-1 win over West Ham United and needs to be assessed before the reunion with Rafael Benitez at Anfield.
Henderson, who was an unused substitute against the Hammers, has featured in training throughout the week and is available to Jürgen Klopp.
“Everybody saw Millie got a real knock in the last game. That still hurts a little bit. We will see how that improves. It’s not an injury but it’s a little issue,” the manager explained at his pre-match press conference.
“Hendo is fine, he trained completely normally – all good.