Mane missed the weekend win over Huddersfield Town due to a hand injury sustained on international duty, but has since returned to full training.
Milner and Wijnaldum both played at the John Smith’s Stadium, with the former overcoming a hamstring issue to start while the former picked up a knock after coming on at half-time.
However, Jürgen Klopp confirmed to Liverpoolfc.com on Tuesday that the trio are available for the clash with Red Star.
The boss said: "Millie looks fine and should be OK, Gini got a knock on his Achilles but should be OK and Sadio trained and should be fine.