The Reds make their first trip to the Pirelli Stadium on Tuesday night for the second round clash, against Nigel Clough’s newly-promoted Championship side.
Joel Matip is expected to make his competitive debut for the Reds having been on the bench for their opening two Premier League fixtures, while Marko Grujic is likely to get his first start in midfield.
Divock Origi should also start, as will Emre Can if he can shake off a back complaint, while the likes of Danny Ings and Lazar Markovic will hope to feature, having not done so as of yet this season.