The manager opted for seven changes to his starting line-up at the iPro Stadium, including full competitive debuts for Marko Grujic and Loris Karius.
Ovie Ejaria also made his senior bow from the bench, Danny Ings was introduced for a first appearance of the season and Emre Can clocked up game time after injury.
There was no dip in Liverpool’s quality, though, and they followed up Premier League victories over Leicester City and Chelsea by eliminating the Rams with a 3-0 result.
Asked to assess the efforts of those who came in, Klopp told Liverpoolfc.com: “For Divock [Origi], the goal was good.