The Reds currently have only two senior natural choices for the position in Dejan Lovren and Virgil van Dijk, with Joe Gomez and Joel Matip injured.
Tonight’s trip to Wolverhampton Wanderers is the first of four Premier League matches in a fortnight for Klopp’s table-topping side.
Assessing his cover for central defence, the manager confirmed Fabinho as back-up and explained why a three-man system using two midfielders in deeper roles - a plan deployed at Brighton and Hove Albion last season - is also an alternative.
“I hope Dejan can play them all but I don’t know in the moment.