Jordan Henderson comes into the starting XI for the 233rd Merseyside derby with Everton, while Firmino is fit enough to be part of the squad but Divock Origi continues in attack.
“Millie just felt a little bit his hamstring,” Klopp told Sky Sports.
“If Millie gives a warning sign… I think he would have been fine but the last two days he felt it still. So there is no reason for risk, especially when we have options on the bench, which we had in the last game.
“Hendo is a very, very important player for us, so it’s good he can be back.