The Reds can qualify for the knockout rounds and secure top spot in Group E with a victory over Napoli at Anfield on Wednesday night.
Despite reaching the last 16 for the past two seasons and lifting the trophy in June, Klopp insists the competition's mystique remains fully intact for all involved at the club.
The boss told Liverpoolfc.com: "It's great. We just don't get used to it, that's how it is. It's nice and it's always exciting.
"An incredibly strong opponent in a difficult situation - we know that - but that makes them even more dangerous for us because they don't play in Italy now, nobody speaks about the problems, they speak about the opportunity to go through.