Jurgen Klopp has promised Liverpool will attack their final Champions League group game as the finances involved mean it would be unprofessional to give it up.
Liverpool qualified for the knockout stages last week when they beat Ajax and there is little doubt Klopp will take the opportunity to give some of his senior players a rest.
It is going to present an opportunity for some of the younger members of the squad, with Leighton Clarkson and Jake Cain potentially set to make their debuts against FC Midtjylland.
Rhys Williams, who has impressed when called upon in Europe this season, is also likely to start.