Young Lions boss Aidy Boothroyd confirmed after his side’s 2-1 victory that Solanke had started as a substitute due to a toe complaint that caused him to miss Saturday’s friendly with Romania.
But the Reds striker made a telling contribution after being introduced at Bramall Lane, heading home Ben Chilwell’s cross late on to maintain the hosts’ five-point lead at the top of their qualification group.
Solanke’s three club-mates in the senior England set-up all featured in their 1-1 friendly draw with Italy.
Alex Oxlade-Chamberlain started at Wembley and completed an hour before being replaced by Adam Lallana, while Jordan Henderson came on with 17 minutes remaining.