There were victories for Sadio Mane, Andy Robertson, Takumi Minamino and Caoimhin Kelleher.
Minamino featured for 78 minutes in Japan's 2-1 victory over Australia in a 2022 World Cup qualifier and played a key role in creating Ao Tanaka's opener.
There was a clean sheet for Kelleher, meanwhile, as the Republic of Ireland beat Qatar 4-0 in a friendly.
In World Cup qualifying, Robertson captained Scotland to an important 1-0 win over the Faroe Islands, while Mane's Senegal defeated Namibia 3-1.
Jordan Henderson came off the bench after 76 minutes at Wembley in England's 1-1 draw with Hungary.