Trent Alexander-Arnold, Virgil van Dijk, Andy Robertson and Sadio Mane were all included in the XI for 2018-19, which is decided by a poll of all top-flight players and was revealed on Thursday.
Three of that foursome are in the running for individual PFA honours, too.
Alexander-Arnold is on the six-man shortlist for the Young Player of the Year award, while Van Dijk and Mane are in contention for the Players’ Player of the Year prize that went to Mohamed Salah 12 months ago.
The winners of those accolades will be revealed at the 2019 PFA Awards in London on Sunday.