The Europa League group stage gets under way on Thursday with Premier League trio Brighton, Liverpool and West Ham and Scottish side Rangers all involved in the competition.
BBC Sport takes a look at the key things to watch out for.
Brighton heading into the unknown
There will be six teams making their Europa League debut this season, with Brighton one of them.
The Seagulls continue to look impressive under Roberto De Zerbi and, just like they did in the Premier League last season, they will be confident of causing a few upsets as they make their debut in Europe.