Moussa Niakhate and substitute Kunde Malong scored as Mainz secured a 2-0 victory away to Eintracht Frankfurt to boost their chances of avoiding relegation.
The result sees Mainz remain in 15th place in the Bundesliga, while Frankufrt are 11th.
Filip Kostic shot narrowly wide for Frankfurt before Liverpool loanee Taiwo Awoniyi should have done better from close range for Mainz.
Niakhate put Mainz ahead just before half time with an emphatic header and Malong made it 2-0 in the second half as he finished calmly.