The European heavyweights drew 0-0 at Anfield in the first leg of their last-16 clash, meaning any margin of victory or a score draw will send the Reds through.
We've picked out three key battles that could help decide the finely-balanced tie in Germany...
Robert Lewandowski v Virgil van Dijk
Robert Lewandowski has been Bayern's top scorer in each of the last four seasons - 2017-18 (41), 2016-17 (43), 2015-16 (42), 2014-15 (25) - and his brace in the weekend's 6-0 thrashing of Wolfsburg saw the Polish striker set a new record as the top foreign goalscorer in Bundesliga history.