Klopp reached the dugout milestone against Southampton on Saturday, with that total accumulated from spells with FSV Mainz, Borussia Dortmund and the Reds.
The German has won almost half of those games – overseeing 296 victories – with 158 draws and 146 defeats.
The 3-0 success against Saints, achieved courtesy of a Wesley Hoedt own goal and further first-half efforts from Joel Matip and Mohamed Salah, increased Liverpool’s unbeaten streak at Anfield in the Premier League to 24 matches (won 16, drawn eight).
That represents their best such run since August 2009 – 31 games.
This is the third time that Liverpool have won six consecutive league fixtures to start a top-flight campaign, having also done so in 1978-79 and 1990-91.