Manchester City midfielder Kevin de Bruyne is expected to be fit despite needing treatment following a heavy challenge during the League Cup win against Bournemouth.
Aymeric Laporte is unavailable due to Covid regulations, while Nicolas Otamendi is also sidelined.
Leicester City midfielder Wilfried Ndidi could miss up to three months with an abductor injury.
Ricardo Pereira remains out but Jonny Evans could feature following a ban.
LAWRO'S PREDICTION
Manchester City got the job done against Wolves on Monday in what was a tricky opener for them.
Leicester have won two out of two so far but the injured Wilfred Ndidi is going to be a big miss for them at the back, where he has been filling in for them.