For the KC Royals, Ian Kennedy follows Duffy in game two, and Jason Hammel gets the nod for game three.
Duffy was impressive in his two World Baseball Classic starts, finishing with a 2-0 record and 1.13 ERA. He allowed eight hits, struck out eight, and allowed just one earned run in his eight innings of work for the United States.
Friday, Duffy returned to spring training where he allowed three runs in six innings in a 4-3 loss to Seattle.
Last season, Duffy led the Royals starters with a 3.