Sano, who homered and drove in four runs in Friday's win, erased a 2-0 deficit with a blast into the left-field bullpen in the third inning off Royals starter Jason Hammel. Sano now has 14 RBIs against the Royals this season.
For the second straight start, Hammel could not escape the fourth inning. He went three-plus and gave up six hits and five runs, his ERA ballooning to 6.65.
Twins starter Phil Hughes was marginally better, lasting 5 2/3 innings while giving up 10 hits and four runs.
MOMENTS THAT MATTERED
Pressly shuts the door: The Royals threatened in the sixth with back-to-back two-out singles, including an RBI single from Alcides Escobar to knock out Hughes and make it a two-run game.