4:25 p.m. ET | FOX
Matchup rating: 37.1 | Spread: LAC -3.5 (43.5)
What to watch for: The Chiefs will try to keep as many of their regulars out of harm's way after clinching the AFC's No. 1 playoff seed last week. So Chargers quarterback Justin Herbert is in line for a big day. He got his NFL career started in Week 2 against the Chiefs by throwing for 311 yards and a touchdown in an overtime defeat. -- Adam Teicher
Bold prediction: Herbert will finish strong with a 400-plus-yard game.