Mahomes, who won the award in 2018, is listed at +500 by DraftKings.
Mahomes, 25, is expected to be motivated after throwing for 4,740 yards and 38 touchdowns during the regular season before enduring one of the worst games of his NFL career in last Sunday’s 31-9 loss to the Tampa Bay Buccaneers. He completed 26 of 49 passes for 270 yards with no touchdowns and two interceptions in Super Bowl LV.
Reigning NFL MVP Aaron Rodgers of the Green Bay Packers resides at +800 to capture his fourth such award.