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AP staff “Thursday Night Football” preview, predictions and discussion for Week 3

won’t play until Sunday, when they host the Chicago Bears (+12.5) on GEHA Field at Arrowhead Stadium.

But Week 3 of the NFL season kicks off with the New York Giants (+10.5)

on the road against the San Francisco 49ers (-10.5) on “Thursday Night Football.”

The 49ers opened the season with two road games in which they walloped the Pittsburgh Steelers (+2.5)

22-7 and dispatched the Los Angeles Rams (+3) 30-23 in a divisional matchup. In their home opener, they’ll face the Giants, who began their season by falling to the Dallas Cowboys (-12.