SANTA CLARA, Calif. -- Already missing one of their top three receivers, the San Francisco 49ers lost wideouts Deebo Samuel and Brandon Aiyuk to an illness and a right knee injury, respectively, on Sunday against the Kansas City Chiefs.
Of more pressing immediate concern was the knee injury to Aiyuk. With 48 seconds left in the second quarter, Niners quarterback Brock Purdy found Aiyuk between two Chiefs defenders for a gain of 15 yards. Chiefs defensive backs Chamarri Conner and Trent McDuffie converged on Aiyuk as he took a low hit, leaving his knee in a precarious position.