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Thursday Night Football picks and open thread for Week 1

Related Topics: Thursday Night Football

Thursday Night Football kicks off tonight at 8:15 p.m. EST as the Kansas City Chiefs (-4)

host the Detroit Lions (+4) at Arrowhead Stadium. The Chiefs are 4.5-point favorites, according to our friends at DraftKings Sportsbook, and the total is set at 53.5 points.

Detroit will try to knock off the defending champs in the NFL’s first regular season game of 2023. Kansas City is expected to play without its two best players not named Patrick Mahomes -- tight end Travis Kelce (hyperextended knee) and defensive tackle Chris Jones (contract holdout) are unlikely to suit up.