The 49ers and Cardinals face off on Monday Night Football.
The NFL rolls right along into Monday Night Football with a classic NFC West matchup between the San Francisco 49ers (-10)
and the Arizona Cardinals (+10). It’s an interesting matchup for the NFC West, especially for the Niners with the additional of Christian McCaffery to their offense. McCaffery only has three games with the 49ers but he’s already found the endzone three times.
On the flipside for the Cardinals, they’re going to be without starting quarterback Kyle Murray as Colt McCoy is going to be starting for them again.