RB Leipzig's Bundesliga title bid came to a grinding halt after a second consecutive loss.
Bayern Munich look set to wrap up another Bundesliga title after nearest challengers RB Leipzig lost 3-0 at Werder Bremen.
Ralph Hasenhuttl's side, beaten at home by Wolfsburg last time out, succumbed to goals from Zlatko Junuzovic, Florian Grillitsch and substitute Florian Kainz.
It leaves them still 10 points behind Bayern, whose game in hand comes against Borussia Monchengladbach on Sunday.
Junuzovic broke the deadlock 10 minutes before half-time, somehow finding space for a shot on the edge of a crowded penalty area and picking out the top corner.