Andriy Shevchenko's side have been in strong scoring form, while the visitors lead by Cristiano Ronaldo are always dangerous in the final third
The top two sides in Group B meet in Kiev with Ukraine hosting Portugal in a key game in Euro 2020 qualifying.
Both teams are unbeaten and in strong form heading into the clash, with their previous meeting back in March ending goalless in Lisbon.
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Ukraine have won their three home games in the group without conceding a goal with their most recent success coming against Lithuania on Friday with a 2-0 scoreline.