The away side needs three points to keep its playoff hopes alive, but that won't be an easy task against the defending champions
Tigres fell short in a top-of-the table clash with Toluca last weekend, and will try to bounce back Saturday when they host Cruz Azul.
The defending champions fell 1-0 to the Red Devils at the Estadio Nemesio Diez, dropping down to fourth place in the process.
Facing a wounded giant like Tigres is a daunting prospect for Cruz Azul, which badly needs a win at the Estadio Universitario, known as El Volcan, to keep its season alive.