The star striker looking to break Mexico's all-time scoring record is fit while Juan Carlos Osorio elected not to start the Real Sociedad man.
Juan Carlos Osorio has stayed true to his reputation and made a number of changes for Mexico's World Cup qualification match against Trinidad and Tobago.
The coach has made five changes from Mexico's 2-0 victory over Costa Rica and also looks set to deploy a different formation than the 4-3-3 El Tri played in the Estadio Azteca.
Javier "Chicharito" Hernandez, who left the Costa Rica game with an injury, is fit to start, but Carlos Vela has been dropped to the bench.