Hedgardo Marin, Elias Hernandez and substitute Orbelin Pineda guided Mexico against El Salvador on Sunday.
Mexico made a winning start to their CONCACAF Gold Cup title defence after overpowering El Salvador 3-1 in their Group C opener.
The defending champions claimed their seventh Gold Cup crown in 2015 and they took a step towards another trophy thanks to first international goals from Hedgardo Marin and Orbelin Pineda, and Elias Hernandez's effort, in San Diego on Sunday.
With Mexico's regular stars afforded a break following the Confederations Cup in Russia, domestic-based players – aside from Erick Torres who plays in the United States – have been given a chance to shine in the country's bid for back-to-back Gold Cups.