Medeama coach Samuel Boadu believes Hearts of Oak's matchday one defeat in the Ghana Premier League could inspire the side to fight for all three points in their matchday two encounter on Sunday.
The two sides come into the fixture at Tarkwa's Akoon Park on contrasting form.
Whereas Medeama registered a 3-1 away win over Ebusua Dwarfs, Hearts suffered a disappointing 1-0 home loss to Berekum Chelsea.
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"We are playing against one of the finest teams in Ghana and Africa and it will be ridiculous to underrate them," Boadu told his club's official website.