The Sweden international will serve a three-match ban after his dismissal in a 3-0 defeat to the Red Devils was upheld by the Football Association
Sunderland midfielder Sebastian Larsson has had an appeal against his red card versus Manchester United rejected by the Football Association.
The 31-year-old was sent off by referee Craig Pawson in the first half of the 3-0 Premier League loss to Jose Mourinho's side after a challenge on United's Ander Herrera.
Manager David Moyes was frustrated with the decision and Sunderland promptly appealed, but the FA has upheld the decision.
"An Independent Regulatory Commission has rejected a wrongful dismissal claim from Sunderland's Sebastian Larsson," it said in a statement.