The duo picked up injuries in the quarter-final tie against Italy and the Mannschaft boss is unable to predict whether or not they will be available in the next stage
Germany coach Joachim Low was unsure if Sami Khedira or Mario Gomez would be available for his side's Euro 2016 semi-final.
Gomez helped set up the opener for Mesut Ozil, whose effort was cancelled out by a Leonardo Bonucci penalty, before coming off in the second half.
Low was uncertain as to whether the duo would be fit to face either France or Iceland in the last four on Thursday.