Kaizer Chiefs will be the hosts in a league game against struggling AmaZulu on Saturday night.
Three points are vital for both teams - with Chiefs eager to stretch their lead at the top of the log and Usuthu desperate to move from the bottom of the standings.
A win for Chiefs will see them open a 10-point lead over Mamelodi Sundowns while victory for the Durban-based side will see them move to 23 points and above the relegation zone depending on how Baroka and Black Leopards play this weekend.