Real Madrid attacker Isco has withdrawn from the Spain squad after suffering a thigh injury in the 5-0 win over Costa Rica, and is a doubt for this weekend's Madrid derby.
The 25-year-old was forced off after just 65 minutes of the victory, and now will play no part in the upcoming friendly encounter with World Cup hosts Russia. He signalled to the bench to be taken off after colliding with Kendall Watson, and was replaced by Marco Asensio.
Isco has left the Spain training camp and will not travel to St Petersburg with the rest of the squad, instead returning to Madrid where he will be treated by the club's medical team.