A first-half blitz from the hosts, including two from Atleti boss Diego's son, sent the champions home from Stadio Luigi Ferraris with their tail between their legs
Giovanni Simeone netted twice to help Genoa to a shock 3-1 win over leaders Juventus in Sunday's Serie A encounter at the Stadio Luigi Ferraris.
The Argentine had failed to score in his last six league outings, but rediscovered his touch as Juve suffered a nightmare opening half an hour during which they conceded three times and left themselves too much to do.
Simeone opened the scoring after just three minutes with a finish from close range, doubling his tally shortly after with a glancing header.