Julian Draxler will not feature for Germany in their international friendly against Russia after being granted permission to depart the squad on compassionate leave.
The 25-year-old has left the group to spend time with his family, though the exact reason for his exit has not been disclosed.
Draxler could yet re-join the group for the Uefa Nations League clash against Netherlands on November 19 but it is yet unclear whether that option will be taken.
No replacement has been called up by manager Joachim Low.
Writing in The Players' Tribune in the summer, Draxler revealed the strong attachment he has to his family and told of the sacrifices he has made to make his football dream a reality.