Diego Simeone's men leapfrogged Barcelona into pole position in the Spanish top flight, with the Frenchman and Belgian smashing home the decisive goals.
Real Madrid may have captured the spotlight this weekend with a thumping win in Zinedine Zidane's first match in charge, but it was its cross-city rival Atletico Madrid that leads La Liga following a 2-0 victory at Celta Vigo on Sunday.
Antoine Griezmann's 14th goal of the campaign and Yannick Ferreira Carrasco's strike 10 minutes from time helped Diego Simeone's men to record a 10th win from their past 12 league outings on a sodden night at Balaidos.