Barcelona are 19 unbeaten La Liga games on the road (W14 D5), scoring in all of them and keeping a clean sheet on 10 occasions.
Valverde, meanwhile, completely overhauls his side following the 2-1 win over Valencia as only ter Stegen, Coutinho and Paulinho keep their spots. Messi, Suarez, Alba, Roberto and Umtiti all drop to the bench, with Gerard Pique and Sergio Busquets not in the squad.
Celta boss Juan Carlos Unzue makes three changes to the side defeated 1-0 by Leganes at the weekend, with both Hugo Mallo and Pablo Hernandez suspended, whilst Cabral drops to the bench.