Sevilla boss Julen Lopetegui rings the changes after resting key players for his side’s lost to lowly Elche in LaLiga at the weekend. Navas, Kounde, Carlos and Acuna form the defence with Jordan, Fernando and Rodriguez starting in the centre of the park. En-Nesyri leads the line for the visitors as Ocampos and Suso start on the wings.
Dortmund are substantially weaker than they were for the first leg of this Champions League tie. Jadon Sancho, Gio Reyna and Raphael Guerreiro all miss out despite facing late fitness tests whilst Axel Witsel and Manuel Akanji remain long term absentees.