Ernesto Valverde's side are seeking to cement their position atop La Liga with a victory over dangerous opponents at Camp Nou
Barcelona go into Matchday 12 of La Liga top of the Primera Division standings, boasting 24 points from 11 matches, three more than city rivals Espanyol, who surprisingly sit second.
Ahead of their weekend match with Real Betis, they have also moved a step closer to the last-16 stage of the Champions League. A 1-1 draw against Inter on Tuesday pushed them to the brink, though Mauro Icardi’s late equaliser ensured they will have to wait until the next round of games to secure a knockout berth.