Asante Kotoko suffered a home defeat in the Ghana Premier League by a 2-1 defeat to Medeama in Obuasi on Saturday.
Emmanuel Gyamfi scored first for the Porcupine Warriors but replies from Prince Opoku and Richard Boadu for the Yellow and Mauves handed the visitors full points in the matchday 21 fixture at the Len Clay Stadium.
This was their first defeat in Obuasi since moving base from Accra for the second round of the competition, and Kotoko have lost first position on the league table to Medeama who were fourth coming into the tie.
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Kotoko coach Mariano Barreto made two changes to the side that started against Great Olympics in the previous games.