The Belgium international midfielder will miss this week's pivotal encounter with the Catalan club, as will Marcelo Brozovic and Ivan Perisic
Radja Nainggolan will miss Inter's clash with Barcelona this weekend after suffering a sprained ankle.
Nainggolan sustained the injury during the weekend's Milan derby, which Inter won 1-0 thanks to Mauro Icardi's injury-time strike.
The Belgium midfielder underwent tests on Monday after he was forced off in the aftermath of a running battle with AC Milan midfielder Lucas Biglia, and it has been confirmed that he will miss a number of weeks, thus ruling him out of the trip to Camp Nou.