The Indianapolis Colts (0-2) visit the Tennessee Titans (1-1) at 1 p.m. EDT Sunday in an AFC South matchup.
The Colts are facing uncertainty at quarterback in the wake of Carson Wentz's ankle injuries. Jacob Eason or Brett Hundley may start. The Colts are also shorthanded along the offensive line.
The Titans are led by quarterback Ryan Tannehill, with wrecking ball running back Derrick Henry and wide receivers A.J. Brown and Julio Jones.
Here's a nugget from IndyStar's Nat Newell: Only 2.6% of the teams that started 0-3 made the playoffs under the 12-team format.