INDIANAPOLIS -- Indianapolis Colts starting center Khaled Holmes has been ruled out for Monday's game at the Carolina Panthers because of a neck injury. He suffered the injury in the first half of the Colts' Week 7 loss to the New Orleans Saints.
Second-year player Jonotthan Harrison will start against the Panthers.
"Coach [Chuck Pagano] always says prepare as if you’re a starter, you never know when your number’s going to be called," Harrison said Saturday.