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Indianapolis Colts G Quenton Nelson to miss first career start Sunday vs. Miami with ankle injury

INDIANAPOLIS - Colts All-Pro guard Quenton Nelson's NFL playing streak is coming to an end at 51 games.

Nelson will miss his first game since entering the NFL as the No. 6 pick in the 2018 draft Sunday at Miami due to a high right ankle sprain, coach Frank Reich said. Nelson suffered the ankle injury in the first half of the Colts Week 3 loss at Tennessee.

Losing Nelson, an All Pro in each of his first three seasons, is significant blow to an already-struggling offensive line for the Colts. His 75.